HiSCR 1.02

Updated journals

• Nat Neurosci Feb 2006
• EMBO J Feb 2006
• Blood Epub
• Oncogene 25 (4)
• Dev 133 (4)
• Nat Rev Mol Cell Biol 7 (2)
• Current Biol 16 (2)

Stem Cells

• Cao R, Bjorndahl MA, Gallego MI, et al. Hepatocyte growth factor is a novel lymphangiogenic factor with an indirect mechamism of action. Blood 2006, PubMed ID: 16424394
  




• Luschnig S, Batz T, Armbruster K, et al. serpentine and vermiform Encode Matrix Proteins with Chitin Binding and Deacetylation Domains that Limit Tracheal Tube Length in Drosophila. Curr Biol 2006, 16 (2): 186-94. PubMed ID: 16431371
  
• Wang S, Jayaram SA, Hemphala J, et al. Septate-junction-dependent luminal deposition of chitin deacetylases restricts tube elongation in the Drosophila trachea. Curr Biol 2006, 16 (2): 180-5. PubMed ID: 16431370
  
• Ma C, Benink HA, Cheng D, et al. Cdc42 activation couples spindle positioning to first polar body formation in oocyte maturation. Curr Biol 2006, 16 (2): 214-20. PubMed ID: 16431375
  
• Cayuso J, Ulloa F, Cox B, et al. The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity. Development 2006, 133 (3): 517-28. PubMed ID: 16410413
  
• Hoch RV and Soriano P. Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. Development 2006, 133 (4): 663-73. PubMed ID: 16421190
  
• Kele J, Simplicio N, Ferri AL, et al. Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development 2006, 133 (3): 495-505. PubMed ID: 16410412
  
• Liu H, Strauss TJ, Potts MB, et al. Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1. Development 2006, 133 (4): 641-50. PubMed ID: 16421192
  
• Mishra SK, Braun N, Shukla V, et al. Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation. Development 2006, 133 (4): 675-84. PubMed ID: 16436623
  
• Narbonne P and Roy R. Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling. Development 2006, 133 (4): 611-9. PubMed ID: 16407400
  
• Provot S, Kempf H, Murtaugh LC, et al. Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation. Development 2006, 133 (4): 651-62. PubMed ID: 16421188
  
• Wu S, Wu Y and Capecchi MR. Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development 2006, 133 (4): 581-90. PubMed ID: 16407399
  
• Chen JC, Hottes AK, McAdams HH, et al. Cytokinesis signals truncation of the PodJ polarity factor by a cell cycle-regulated protease. Embo J 2006, 25 (2): 377-86. PubMed ID: 16395329
  
• Garcia Z, Kumar A, Marques M, et al. Phosphoinositide 3-kinase controls early and late events in mammalian cell division. Embo J 2006, PubMed ID: 16437156
  
• Guenette S, Chang Y, Hiesberger T, et al. Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. Embo J 2006, 25 (2): 420-31. PubMed ID: 16407979
  
• Zheng X, Zugates CT, Lu Z, et al. Baboon/dSmad2 TGF-beta signaling is required during late larval stage for development of adult-specific neurons. Embo J 2006, PubMed ID: 16437159
  
• Kessaris N, Fogarty M, Iannarelli P, et al. Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat Neurosci 2005, PubMed ID: 16388308
  
• Ziv Y, Ron N, Butovsky O, et al. Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood. Nat Neurosci 2006, PubMed ID: 16415867
  
• Li X, Deng W, Nail CD, et al. Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation. Oncogene 2006, 25 (4): 609-21. PubMed ID: 16158046
  
• Zou GM, Chen JJ and Ni J. LIGHT induces differentiation of mouse embryonic stem cells associated with activation of ERK5. Oncogene 2006, 25 (3): 463-9. PubMed ID: 16247486

General Readings

• Critical nodes in signalling pathways: insights into insulin action. Nature Reviews Molecular Cell Biology 7, 85-96
• Complex networks orchestrate epithelial–mesenchymal transitions. Nature Reviews Molecular Cell Biology 7, 131-142
• Not so divided: the common basis of plant and animal cell division. Nature Reviews Molecular Cell Biology 7, 147-152
• Mapping normal and cancer cell signalling networks: towards single-cell proteomics Nature Reviews Cancer 6, 146-155 The author argues the possible use of SINGLE cell proteomics to dissection singal pathways invovled in the cancer development and/or progression. The drug-resistant cell was their target, that may be just functional cancer stem cells. With the recent progress in singel cell isolation of breast cancer stem cells, it becomes possible. Question become how one could examine the cell's phenotype in vivo while ananlyze its proteome?
• Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy Nature Reviews Cancer 6, 117-129
  
• Bacher U, Haferlach T, Schoch C, et al. NRAS mutations in AML: biology, cytogenetics, and prognosis - a study on 2502 patients. Blood 2006, PubMed ID: 16434492
  
• Levine RL, Belisle C, Wadleigh M, et al. X-inactivation based clonality analysis and quantitative JAK2V617F assessment reveals a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F negative ET and MMM patients with clonal hematopoiesis. Blood 2006, PubMed ID: 16434490
  
• Kobayashi S, Isotani A, Mise N, et al. Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the x-linked gene, rhox5/pem, at preimplantation stages. Curr Biol 2006, 16 (2): 166-72. PubMed ID: 16431368
  
• Nie Z, Hirsch DS, Luo R, et al. A BAR Domain in the N Terminus of the Arf GAP ASAP1 Affects Membrane Structure and Trafficking of Epidermal Growth Factor Receptor. Curr Biol 2006, 16 (2): 130-9. PubMed ID: 16431365
  
• Smits VA, Reaper PM and Jackson SP. Rapid PIKK-Dependent Release of Chk1 from Chromatin Promotes the DNA-Damage Checkpoint Response. Curr Biol 2006, 16 (2): 150-9. PubMed ID: 16360315
  
• Armant DR, Kilburn BA, Petkova A, et al. Human trophoblast survival at low oxygen concentrations requires metalloproteinase-mediated shedding of heparin-binding EGF-like growth factor. Development 2006, 133 (4): 751-9. PubMed ID: 16407398
  
• Knapp JR, Davie JK, Myer A, et al. Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size. Development 2006, 133 (4): 601-10. PubMed ID: 16407395
  
• Liu H, Strauss TJ, Potts MB, et al. Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1. Development 2006, 133 (4): 641-50. PubMed ID: 16421192
  
• Seth A, Culverwell J, Walkowicz M, et al. belladonna/(lhx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain. Development 2006, 133 (4): 725-35. PubMed ID: 16436624
  
• Erber R, Eichelsbacher U, Powajbo V, et al. EphB4 controls blood vascular morphogenesis during postnatal angiogenesis. Embo J 2006, PubMed ID: 16424904
  
• Goardon N, Lambert JA, Rodriguez P, et al. ETO2 coordinates cellular proliferation and differentiation during erythropoiesis. Embo J 2006, 25 (2): 357-66. PubMed ID: 16407974
  
• Kharkovets T, Dedek K, Maier H, et al. Mice with altered KCNQ4 K(+) channels implicate sensory outer hair cells in human progressive deafness. Embo J 2006, PubMed ID: 16437162
  
• Miserey-Lenkei S, Couedel-Courteille A, Del Nery E, et al. A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint. Embo J 2006, 25 (2): 278-89. PubMed ID: 16395330
  
• He W, Lam TK, Obici S, et al. Molecular disruption of hypothalamic nutrient sensing induces obesity. Nat Neurosci 2006, PubMed ID: 16415870
  
• Marmigere F, Montelius A, Wegner M, et al. The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons. Nat Neurosci 2006, PubMed ID: 16429136
  
• Gaestel M. MAPKAP kinases - MKs - two's company, three's a crowd. Nat Rev Mol Cell Biol 2006, PubMed ID: 16421520
  
• Kobayashi Y, Ohtsuki M, Murakami T, et al. Histone deacetylase inhibitor FK228 suppresses the Ras-MAP kinase signaling pathway by upregulating Rap1 and induces apoptosis in malignant melanoma. Oncogene 2006, 25 (4): 512-24. PubMed ID: 16186804
  
• Li X, Luwor R, Lu Y, et al. Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells. Oncogene 2006, 25 (4): 525-35. PubMed ID: 16170346