Hightlights in stem cell research 2006-1

Jan 15-Jan 22, 2006

Updated Jounals
--Blood Read more
--Cancer Research Read more
--OncogeneRead more
--Nat Rev Genet Read more
--PNAS Read more
--Molecular cell Read more

Stem cell
--Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: Effect on long term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination. Blood published 19 January 2006
--Hepatocyte growth factor is a novel lymphangiogenic factor with an indirect mechamism of action. Blood published 19 January 2006
--Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells. Blood. 2006 Jan 12
--Down-Regulation of Stem Cell Genes, Including Those in a 200-kb Gene Cluster at 12p13.31, Is Associated with In vivo Differentiation of Human Male Germ Cell Tumors. Cancer Res. 2006 Jan 15;66(2):820-7.
--LIGHT induces differentiation of mouse embryonic stem cells associated with activation of ERK5. Oncogene. 2006 Jan 19;25(3):463-9.
--ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable PNAS published January 17, 2006
--A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies PNAS published January 17, 2006
--Distribution of histone H3.3 in hematopoietic cell lineages PNAS 2006 103: 574-579; published online before print January 5 2006
--Stat5a/b are essential for normal lymphoid development and differentiation PNAS published January 17, 2006
--Xbves is a regulator of epithelial movement during early Xenopus laevis development PNAS 2006 103: 614-619; published online before print January 9 2006
--Germ-line induction of the Caenorhabditis elegans vulva PNAS 2006 103: 620-625; published online before print January 5 2006
--Antagonistic effect of CCAAT enhancer-binding protein- and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors PNAS 2006 103: 672-677; published online before print January 9 2006
--Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission PNAS 2006 103: 714-719; published online before print January 6 2006
--Natural variation and genetic covariance in adult hippocampal neurogenesis
PNAS 2006 103: 780-785; published online before print January 9 2006
--Calnexin is essential for rhodopsin maturation, ca(2+) regulation, and photoreceptor cell survival. Neuron. 2006 Jan 19;49(2):229-41

General Readings
--Rapamycin Disrupts Cyclin/Cyclin-Dependent Kinase/p21/Proliferating Cell Nuclear Antigen Complexes and Cyclin D1 Reverses Rapamycin Action by Stabilizing These Complexes. Cancer Res. 2006 Jan 15;66(2):1070-80.
--Antitumor Activity of Epidermal Growth Factor Receptor-Related Protein Is Mediated by Inactivation of ErbB Receptors and Nuclear Factor-{kappa}B in Pancreatic Cancer. Cancer Res. 2006 Jan 15;66(2):1025-32.
--Restoring e-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. Cancer Res. 2006 Jan 15;66(2):944-50
--Angiopoietin 2 Induces Glioma Cell Invasion by Stimulating Matrix Metalloprotease 2 Expression through the vß1 Integrin and Focal Adhesion Kinase Signaling Pathway Cancer Res 2006 66: 775-783
--PTEN Autoregulates Its Expression by Stabilization of p53 in a Phosphatase-Independent Manner. Cancer Res 2006 66: 736-742
--Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53.Oncogene 25: 359-369; advance online publication, September 19, 2005;
--E2F1 stability is regulated by a novel-PKC/p38beta MAP kinase signaling pathway during keratinocyte differentiation. Oncogene. 2006 Jan 19;25(3):430-7.
--REVIEW Towards multidimensional genome annotation. Nat Rev Genet. 2006 Feb;7(2):130-41.
--REVIEW Structural variation in the human genome. Nat Rev Genet. 2006 Feb;7(2):85-97.
--TAF7: A possible transcription initiation check-point regulator PNAS 2006 103: 602-607; published online before print January 9 2006
--A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells PNAS 2006 103: 690-695; published online before print January 6 2006
--Leptin: A potential novel antidepressant PNAS published January 19, 2006
--Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines PNAS published January 17, 2006