CA Stem cell inst gets OK

The $3 billion California initiative for funding stem cell research got ok from California court. But the plaintiffs plan to appeal, another year wait may be necessary. The executives and scientists are extremely happy for the new anyway.

See more news coverage at Science, and MediacalNewsToday.

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BW undergrad B-school ranking 2006

Businessweek just cooked out their inaugural ranking list of Best undergrad B-schools. Interestingly, I found no Harvard, Yale, Columbia, Brown, or Dartmouth in the list. My guess would be that those Ivy League schools do not have a so-called undergrad business degree for undergrads, rather just a major in business. At Michigan, only select sophomores could grasp a BBA degree beared big M through 2 year study at Ross B School.

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Cell Apr 21 2006

Cell Apr 21, 2006

Pten, Tumorigenesis, and Stem Cell Self-Renewal Derrick J. Rossi and Irving L. Weissman 229

Searching Chromatin for Stem Cell Identity. Michael Buszczak and Allan C. Spradling REVIEW 233

Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells Tong Ihn Lee, Richard G. Jenner, Laurie A. Boyer, Matthew G. Guenther, Stuart S. Levine, Roshan M. Kumar, Brett Chevalier, Sarah E. Johnstone, Megan F. Cole, Kyo-ichi Isono, Haruhiko Koseki, Takuya Fuchikami, Kuniya Abe, Heather L. Murray, Jacob P. Zucker, Bingbing Yuan, George W. Bell, Elizabeth Herbolsheimer, Nancy M. Hannett, Kaiming Sun, Duncan T. Odom, Arie P. Otte, Thomas L. Volkert, David P. Bartel, Douglas A. Melton, David K. Gifford, Rudolf Jaenisch, and Richard A. Young 301

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells Bradley E. Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J. Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath, Rudolf Jaenisch, Alexandre Wagschal, Robert Feil, Stuart L. Schreiber, and Eric S. Lander 315

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Cancer Research

Cancer Research
Vol 66, issue 8 , Apr 2006

Meeting Report: Antiangiogenesis and Drug Delivery to Tumors: Bench to Bedside and Back Dan G. Duda Cancer Res 2006 66: 3967-3970

KRAS Mutation Status Is Predictive of Response to Cetuximab Therapy in Colorectal Cancer Astrid Lièvre, Jean-Baptiste Bachet, Delphine Le Corre, Valérie Boige, Bruno Landi, Jean-François Emile, Jean-François Côté, Gorana Tomasic, Christophe Penna, Michel Ducreux, Philippe Rougier, Frédérique Penault-Llorca, and Pierre Laurent-Puig Cancer Res 2006 66: 3992-3995

Id1 Transcription Inhibitor–Matrix Metalloproteinase 9 Axis Enhances Invasiveness of the Breakpoint Cluster Region/Abelson Tyrosine Kinase–Transformed Leukemia CellsMargaret Nieborowska-Skorska, Grazyna Hoser, Lori Rink, Maciej Malecki, Plamen Kossev, Mariusz A. Wasik, and Tomasz Skorski Cancer Res 2006 66: 4108-4116

Multiple Adaptive Mechanisms to Chronic Liver Disease Revealed at Early Stages of Liver Carcinogenesis in the Mdr2-Knockout Mice Mark Katzenellenbogen, Orit Pappo, Hila Barash, Naama Klopstock, Lina Mizrahi, Devorah Olam, Jasmine Jacob-Hirsch, Ninette Amariglio, Gidi Rechavi, Leslie Ann Mitchell, Ron Kohen, Eytan Domany, Eithan Galun, and Daniel Goldenberg Cancer Res 2006 66: 4001-4010

Two-Dimensional Transcriptome Profiling: Identification of Messenger RNA Isoform Signatures in Prostate Cancer from Archived Paraffin-Embedded Cancer Specimens Hai-Ri Li, Jessica Wang-Rodriguez, T. Murlidharan Nair, Joanne M. Yeakley, Young-Soo Kwon, Marina Bibikova, Christina Zheng, Lixin Zhou, Kui Zhang, Tracy Downs, Xiang-Dong Fu, and Jian-Bing Fan Cancer Res 2006 66: 4079-4088.

Targeting Oncogenes to Improve Breast Cancer Chemotherapy Laura A. Christensen, Rick A. Finch, Adam J. Booker, and Karen M. Vasquez Cancer Res 2006 66: 4089-4094.

The Kinase Mirk/Dyrk1B Mediates Cell Survival in Pancreatic Ductal Adenocarcinoma Xiaobing Deng, Daina Z. Ewton, Sheena Li, Asghar Naqvi, Stephen E. Mercer, Steve Landas, and Eileen Friedman Cancer Res 2006 66: 4149-4158.

Development of Real-time Subcellular Dynamic Multicolor Imaging of Cancer-Cell Trafficking in Live Mice with a Variable-Magnification Whole-Mouse Imaging System Kensuke Yamauchi, Meng Yang, Ping Jiang, Mingxu Xu, Norio Yamamoto, Hiroyuki Tsuchiya, Katsuro Tomita, Abdool R. Moossa, Michael Bouvet, and Robert M. Hoffman Cancer Res 2006 66: 4208-4214.

Tumor Imaging Using a Picomolar Affinity HER2 Binding Affibody Molecule Anna Orlova, Mikaela Magnusson, Tove L.J. Eriksson, Martin Nilsson, Barbro Larsson, Ingmarie Höidén-Guthenberg, Charles Widström, Jörgen Carlsson, Vladimir Tolmachev, Stefan Ståhl, and Fredrik Y. Nilsson Cancer Res 2006 66: 4339-4348.

Characterization of a Novel Human Tumor Antigen Interleukin-13 Receptor 2 Chain Koji Kawakami, Masaki Terabe, Mariko Kawakami, Jay A. Berzofsky, and Raj K. Puri Cancer Res 2006 66: 4434-4442.

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Technology transfer office

More than the money Top of pageAbstractTechnology-transfer offices are learning from their mistakes. So should the academics that they serve. Nature 440, 845-846 (13 April 2006) | doi:10.1038/440845b

University challenge. Cambridge is revamping its approach to technology transfer — but will it work? Colin Macilwain reports. Nature 440, 867 (13 April 2006) doi:10.1038/440867a

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Development May 2006

CONTENT

Wellington V. Cardoso and Jining Lü. Regulation of early lung morphogenesis: questions, facts and controversies Development 2006 133: 1611-1624. REVIEW

Marie A. Breau, Thomas Pietri, Olivier Eder, Martine Blanche, Cord Brakebusch, Reinhardt Fässler, Jean P. Thiery, and Sylvie Dufour. Lack of ß1 integrins in enteric neural crest cells leads to a Hirschsprung-like phenotype . Development 2006 133: 1725-1734.

Elaine E. Storm, Sonia Garel, Ugo Borello, Jean M. Hebert, Salvador Martinez, Susan K. McConnell, Gail R. Martin, and John L. R. Rubenstein. Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers Development 2006 133: 1831-1844.

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Reversal of Diabetes in Non-Obese Diabetic Mice

Recently, a series of papers showed Reversal of Diabetes in Non-Obese Diabetic Mice without beta cell regeneration derived from spleen-cell or hematopoietic cells.

Chong AS, Shen J, Tao J, Yin D, Kuznetsov A, Hara M, Philipson LH. Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science. 2006 Mar 24;311(5768):1774-5.
PMID: 16556844 [PubMed - indexed for MEDLINE]

Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D. Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science. 2006 Mar 24;311(5768):1775-8.
PMID: 16556845 [PubMed - indexed for MEDLINE]

Suri A, Calderon B, Esparza TJ, Frederick K, Bittner P, Unanue ER. Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells. Science. 2006 Mar 24;311(5768):1778-80.
PMID: 16556846 [PubMed - indexed for MEDLINE]

Kodama S, Kuhtreiber W, Fujimura S, Dale EA, Faustman DL. Islet regeneration during the reversal of autoimmune diabetes in NOD mice.Science. 2003 Nov 14;302(5648):1223-7.
PMID: 14615542 [PubMed - indexed for MEDLINE]

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